Evaluating Between-Pathway Models with Expression Data
نویسندگان
چکیده
منابع مشابه
Evaluating Between-Pathway Models with Expression Data
Between-pathway models (BPMs) are network motifs consisting of pairs of putative redundant pathways. In this article, we show how adding another source of high-throughput data--microarray gene expression data from knockout experiments--allows us to identify a compensatory functional relationship between genes from the two BPM pathways. We evaluate the quality of the BPMs from four different stu...
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ژورنال
عنوان ژورنال: Journal of Computational Biology
سال: 2010
ISSN: 1066-5277,1557-8666
DOI: 10.1089/cmb.2009.0178